2ROX

TRANSTHYRETIN (ALSO CALLED PREALBUMIN) COMPLEX WITH THYROXINE (T4)

Replaces:  1ROX

Summary for 2ROX

• Entry DOI: 10.2210/pdb2rox/pdb
• Descriptor: TRANSTHYRETIN, SULFATE ION, 3,5,3',5'-TETRAIODO-L-THYRONINE, ... (4 entities in total)
• Functional Keywords: albumin, transport, retinol-binding, vitamin a, amyloid, thyroid hormone, liver, plasma, cerebrospinal fluid, polyneuropathy, polymorphism, disease mutation, thyroxine, prealbumin
• Biological source: Homo sapiens (human)
• Cellular location: Secreted: P02766
• Total number of polymer chains: 2
• Total formula weight: 29204.52

Authors

Wojtczak, A.,Cody, V.,Luft, J.R.,Pangborn, W. (deposition date: 1996-10-23, release date: 1997-04-21, Last modification date: 2023-11-15)

• Primary citation: Wojtczak, A.,Cody, V.,Luft, J.R.,Pangborn, W.; Structures of human transthyretin complexed with thyroxine at 2.0 A resolution and 3',5'-dinitro-N-acetyl-L-thyronine at 2.2 A resolution.; Acta Crystallogr.,Sect.D, 52:758-765, 1996; PubMed: 15299640; DOI: 10.1107/S0907444996003046

Experimental method

X-RAY DIFFRACTION (2 Å)