1RJ6
Crystal Structure of the Extracellular Domain of Murine Carbonic Anhydrase XIV in Complex with Acetazolamide
Summary for 1RJ6
Entry DOI | 10.2210/pdb1rj6/pdb |
Related | 1RJ5 |
Descriptor | Carbonic anhydrase XIV, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | beta-sheet, alpha-helix, zinc enzyme, lyase |
Biological source | Mus musculus (house mouse) |
Total number of polymer chains | 2 |
Total formula weight | 60413.08 |
Authors | Whittington, D.A.,Grubb, J.H.,Waheed, A.,Shah, G.N.,Sly, W.S.,Christianson, D.W. (deposition date: 2003-11-18, release date: 2004-03-09, Last modification date: 2020-07-29) |
Primary citation | Whittington, D.A.,Grubb, J.H.,Waheed, A.,Shah, G.N.,Sly, W.S.,Christianson, D.W. Expression, assay, and structure of the extracellular domain of murine carbonic anhydrase XIV: implications for selective inhibition of membrane-associated isozymes. J.Biol.Chem., 279:7223-7228, 2004 Cited by PubMed: 14660577DOI: 10.1074/jbc.M310809200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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