1RJ6
Crystal Structure of the Extracellular Domain of Murine Carbonic Anhydrase XIV in Complex with Acetazolamide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Carbonic anhydrase XIV | polymer | 261 | 29332.3 | 2 | UniProt (Q9WVT6) Pfam (PF00194) In PDB | Mus musculus (house mouse) | Carbonate dehydratase XIV, CA-XIV |
| 2 | C | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 3 | D | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G22573RC) | |||
| 4 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 5 | A, B | 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE | non-polymer | 222.2 | 2 | Chemie (AZM) | |||
| 6 | water | water | 18.0 | 32 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 260 (UniProt: Q9WVT6)
| PDB | External Database | Details |
|---|---|---|
| His 108 | Gln 124 | see remark 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 58664.7 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1173.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 575.3 | |
| All* | Total formula weight | 60413.1 |
