1RGR

Cyclic Peptides Targeting PDZ Domains of PSD-95: Structural Basis for Enhanced Affinity and Enzymatic Stability

Summary for 1RGR

• Entry DOI: 10.2210/pdb1rgr/pdb
• Descriptor: Presynaptic density protein 95, postsynaptic protein CRIPT peptide, BETA-ALANINE (3 entities in total)
• Functional Keywords: pdz1 domain, structural protein-de novo protein complex, structural protein/de novo protein
• Biological source: Rattus norvegicus (Norway rat); More
• Cellular location: Cell membrane; Peripheral membrane protein: P31016
• Total number of polymer chains: 2
• Total formula weight: 11718.13

Authors

Piserchio, A.,Salinas, G.D.,Li, T.,Marshall, J.,Spaller, M.R.,Mierke, D.F. (deposition date: 2003-11-12, release date: 2004-05-18, Last modification date: 2021-10-27)

• Primary citation: Piserchio, A.,Salinas, G.D.,Li, T.,Marshall, J.,Spaller, M.R.,Mierke, D.F.; Targeting Specific PDZ Domains of PSD-95; Structural Basis for Enhanced Affinity and Enzymatic Stability of a Cyclic Peptide.; Chem.Biol., 11:469-473, 2004; PubMed: 15123241; DOI: 10.1016/j.chembiol.2004.03.013

Experimental method

SOLUTION NMR