1REK
Crystal structure of cAMP-dependent protein kinase complexed with balanol analog 8
Summary for 1REK
Entry DOI | 10.2210/pdb1rek/pdb |
Related | 1ATP 1BX6 1RE8 1REJ |
Descriptor | cAMP-dependent protein kinase, alpha-catalytic subunit, 3-[(3-SEC-BUTYL-4-HYDROXYBENZOYL)AMINO]AZEPAN-4-YL 4-(2-HYDROXY-5-METHOXYBENZOYL)BENZOATE, PENTANAL, ... (4 entities in total) |
Functional Keywords | protein kinase, natural product inhibitor, ligand binding, specifity determinants, conformational malleability, transferase |
Biological source | Mus musculus (house mouse) |
Cellular location | Cytoplasm (By similarity): P05132 |
Total number of polymer chains | 1 |
Total formula weight | 41304.08 |
Authors | Akamine, P.,Madhusudan,Brunton, L.L.,Ou, H.D.,Canaves, J.M.,Xuong, N.H.,Taylor, S.S. (deposition date: 2003-11-06, release date: 2004-02-24, Last modification date: 2023-08-23) |
Primary citation | Akamine, P.,Madhusudan,Brunton, L.L.,Ou, H.D.,Canaves, J.M.,Xuong, N.H.,Taylor, S.S. Balanol analogues probe specificity determinants and the conformational malleability of the cyclic 3',5'-adenosine monophosphate-dependent protein kinase catalytic subunit Biochemistry, 43:85-96, 2004 Cited by PubMed: 14705934PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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