1RD3

2.5A Structure of Anticoagulant Thrombin Variant E217K

Summary for 1RD3

Entry DOI	10.2210/pdb1rd3/pdb
Descriptor	Prothrombin, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
Functional Keywords	hydrolase
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	70056.48
Authors	Carter, W.J.,Myles, T.,Leung, L.L.,Huntington, J.A. (deposition date: 2003-11-05, release date: 2004-05-04, Last modification date: 2023-08-23)
Primary citation	Carter, W.J.,Myles, T.,Gibbs, C.S.,Leung, L.L.,Huntington, J.A. Crystal Structure of Anticoagulant Thrombin Variant E217K Provides Insights into Thrombin Allostery J.Biol.Chem., 279:26387-26394, 2004 Cited by PubMed: 15075325 DOI: 10.1074/jbc.M402364200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation