1QPL
FK506 BINDING PROTEIN (12 KDA, HUMAN) COMPLEX WITH L-707,587
Summary for 1QPL
Entry DOI | 10.2210/pdb1qpl/pdb |
Descriptor | PROTEIN (FK506-BINDING PROTEIN), C32-O-(1-METHYL-INDOL-5-YL) 18-HYDROXY-ASCOMYCIN (3 entities in total) |
Functional Keywords | immunophilin-drug complex, cis-trans isomerase, peptidyl-prolyl isomerase, isomerase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm, cytosol : P62942 |
Total number of polymer chains | 2 |
Total formula weight | 25547.35 |
Authors | Becker, J.W.,Rotonda, J. (deposition date: 1999-05-25, release date: 1999-08-16, Last modification date: 2023-08-16) |
Primary citation | Becker, J.W.,Rotonda, J.,Cryan, J.G.,Martin, M.,Parsons, W.H.,Sinclair, P.J.,Wiederrecht, G.,Wong, F. 32-Indolyl ether derivatives of ascomycin: three-dimensional structures of complexes with FK506-binding protein. J.Med.Chem., 42:2798-2804, 1999 Cited by PubMed: 10425089DOI: 10.1021/jm9806042 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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