1QPL

FK506 BINDING PROTEIN (12 KDA, HUMAN) COMPLEX WITH L-707,587

Summary for 1QPL

• Entry DOI: 10.2210/pdb1qpl/pdb
• Descriptor: PROTEIN (FK506-BINDING PROTEIN), C32-O-(1-METHYL-INDOL-5-YL) 18-HYDROXY-ASCOMYCIN (3 entities in total)
• Functional Keywords: immunophilin-drug complex, cis-trans isomerase, peptidyl-prolyl isomerase, isomerase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm, cytosol : P62942
• Total number of polymer chains: 2
• Total formula weight: 25547.35

Authors

Becker, J.W.,Rotonda, J. (deposition date: 1999-05-25, release date: 1999-08-16, Last modification date: 2023-08-16)

• Primary citation: Becker, J.W.,Rotonda, J.,Cryan, J.G.,Martin, M.,Parsons, W.H.,Sinclair, P.J.,Wiederrecht, G.,Wong, F.; 32-Indolyl ether derivatives of ascomycin: three-dimensional structures of complexes with FK506-binding protein.; J.Med.Chem., 42:2798-2804, 1999; PubMed: 10425089; DOI: 10.1021/jm9806042

Experimental method

X-RAY DIFFRACTION (2.9 Å)