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1Q3E

HCN2J 443-645 in the presence of cGMP

Summary for 1Q3E
Entry DOI10.2210/pdb1q3e/pdb
Related1Q43 1Q5O
DescriptorPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2, CYCLIC GUANOSINE MONOPHOSPHATE (3 entities in total)
Functional Keywordscnbd, c-linker, pacemaker, hcn, channel, cyclic nucleotide, cap, pka, cgmp, ion channel, ligand, transport protein
Biological sourceMus musculus (house mouse)
Cellular locationMembrane; Multi-pass membrane protein: O88703
Total number of polymer chains2
Total formula weight49075.97
Authors
Zagotta, W.N.,Olivier, N.B.,Black, K.D.,Young, E.C.,Olson, R.,Gouaux, J.E. (deposition date: 2003-07-29, release date: 2003-09-09, Last modification date: 2024-02-14)
Primary citationZagotta, W.N.,Olivier, N.B.,Black, K.D.,Young, E.C.,Olson, R.,Gouaux, J.E.
Structural basis for modulation and agonist specificity of HCN pacemaker channels
Nature, 425:200-205, 2003
Cited by
PubMed: 12968185
DOI: 10.1038/nature01922
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.9 Å)
Structure validation

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