1Q3E
HCN2J 443-645 in the presence of cGMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 | polymer | 207 | 24192.8 | 2 | UniProt (O88703) Pfam (PF00027) | Mus musculus (house mouse) | Brain cyclic nucleotide gated channel 2, BCNG-2, Hyperpolarization-activated cation channel 1, HAC-1 |
| 2 | C, D (A, B) | CYCLIC GUANOSINE MONOPHOSPHATE | non-polymer | 345.2 | 2 | Chemie (PCG) PubChem (177270406) PubChem (136759845) PubChem (135398570) PubChem (135402012) PubChem (135415582) PubChem (135530416) PubChem (135566687) PubChem (135612771) PubChem (136122637) PubChem (136183234) PubChem (136183235) PubChem (136239427) PubChem (136268916) PubChem (136454903) PubChem (136454906) PubChem (136488083) PubChem (136488088) PubChem (136499047) PubChem (136678837) PubChem (137218937) PubChem (137234705) PubChem (137279777) PubChem (138399475) PubChem (164162904) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 330 | Chemie (HOH) |
Sequence modifications
A, B: 443 - 645 (UniProt: O88703)
| PDB | External Database | Details |
|---|---|---|
| Gly 439 | - | cloning artifact |
| Ser 440 | - | cloning artifact |
| Ala 441 | - | cloning artifact |
| Met 442 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 48385.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 690.4 | |
| All* | Total formula weight | 49076.0 |
