1PM7
RmlC (dTDP-6-DEOXY-D-XYLO-4-HEXULOSE 3,5-EPIMERASE)STRUCTURE FROM MYCOBACTERIUM TUBERCULOSIS AND INHIBITOR DESIGN. THE APO STRUCTURE.
Summary for 1PM7
Entry DOI | 10.2210/pdb1pm7/pdb |
Descriptor | RFBC, ACETATE ION, GLYCEROL, ... (4 entities in total) |
Functional Keywords | rmlc, beta barrel, main beta sheet structure, structural genomics, psi, protein structure initiative, tb structural genomics consortium, tbsgc, isomerase |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 2 |
Total formula weight | 44976.17 |
Authors | Dong, C.,Naismith, J.H.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2003-06-10, release date: 2003-12-09, Last modification date: 2024-02-14) |
Primary citation | Babaoglu, K.,Page, M.A.,Jones, V.C.,McNeil, M.R.,Dong, C.,Naismith, J.H.,Lee, R.E. Novel inhibitors of an emerging target in Mycobacterium tuberculosis; substituted thiazolidinones as inhibitors of dTDP-rhamnose synthesis. Bioorg.Med.Chem.Lett., 13:3227-3230, 2003 Cited by PubMed: 12951098DOI: 10.1016/S0960-894X(03)00673-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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