1P6B
X-ray structure of phosphotriesterase, triple mutant H254G/H257W/L303T
Summary for 1P6B
Entry DOI | 10.2210/pdb1p6b/pdb |
Descriptor | Parathion hydrolase, ZINC ION, DIETHYL 4-METHYLBENZYLPHOSPHONATE, ... (5 entities in total) |
Functional Keywords | metalloenzyme, tim barrel, nerve agents, hydrolase |
Biological source | Flavobacterium sp. |
Cellular location | Cell membrane ; Peripheral membrane protein : P0A433 |
Total number of polymer chains | 2 |
Total formula weight | 73663.63 |
Authors | Hill, C.M.,Li, W.,Thoden, J.B.,Holden, H.M.,Raushel, F.M. (deposition date: 2003-04-29, release date: 2003-09-16, Last modification date: 2023-11-15) |
Primary citation | Hill, C.M.,Li, W.S.,Thoden, J.B.,Holden, H.M.,Raushel, F.M. Enhanced degradation of chemical warfare agents through molecular engineering of the phosphotriesterase active site. J.Am.Chem.Soc., 125:8990-8991, 2003 Cited by PubMed: 15369336DOI: 10.1021/ja0358798 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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