1OW3
Crystal Structure of RhoA.GDP.MgF3-in Complex with RhoGAP
Summary for 1OW3
Entry DOI | 10.2210/pdb1ow3/pdb |
Descriptor | Rho-GTPase-activating protein 1, Transforming protein RhoA, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | complex, gtpase, gap, transition state, gene regulation-signaling protein complex, gene regulation/signaling protein |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: Q07960 Cell membrane; Lipid-anchor; Cytoplasmic side: P61586 |
Total number of polymer chains | 2 |
Total formula weight | 49759.36 |
Authors | Graham, D.L.,Lowe, P.N.,Grime, G.W.,Marsh, M.,Rittinger, K.,Smerdon, S.J.,Gamblin, S.J.,Eccleston, J.F. (deposition date: 2003-03-28, release date: 2003-05-06, Last modification date: 2023-08-16) |
Primary citation | Graham, D.L.,Lowe, P.N.,Grime, G.W.,Marsh, M.,Rittinger, K.,Smerdon, S.J.,Gamblin, S.J.,Eccleston, J.F. MgF(3)(-) as a Transition State Analog of Phosphoryl Transfer Chem.Biol., 9:375-381, 2002 Cited by PubMed: 11927263DOI: 10.1016/S1074-5521(02)00112-6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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