1ODY
HIV-1 PROTEASE COMPLEXED WITH AN INHIBITOR LP-130
Summary for 1ODY
| Entry DOI | 10.2210/pdb1ody/pdb |
| Descriptor | HIV-1 PROTEASE, 4-[2-(2-ACETYLAMINO-3-NAPHTALEN-1-YL-PROPIONYLAMINO)-4-METHYL-PENTANOYLAMINO]-3-HYDROXY-6-METHYL-HEPTANOIC ACID [1-(1-CARBAMOYL-2-NAPHTHALEN-1-YL-ETHYLCARBAMOYL)-PROPYL]-AMIDE (3 entities in total) |
| Functional Keywords | aspartic protease, retropepsin, retrovirus, hiv, aids |
| Biological source | HIV-1 M:B_HXB2R |
| Total number of polymer chains | 2 |
| Total formula weight | 22202.20 |
| Authors | Kervinen, J.,Lubkowski, J.,Zdanov, A.,Wlodawer, A.,Gustchina, A. (deposition date: 1998-07-13, release date: 1999-02-16, Last modification date: 2023-08-09) |
| Primary citation | Kervinen, J.,Lubkowski, J.,Zdanov, A.,Bhatt, D.,Dunn, B.M.,Hui, K.Y.,Powell, D.J.,Kay, J.,Wlodawer, A.,Gustchina, A. Toward a universal inhibitor of retroviral proteases: comparative analysis of the interactions of LP-130 complexed with proteases from HIV-1, FIV, and EIAV. Protein Sci., 7:2314-2323, 1998 Cited by PubMed: 9827997PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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