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1ODW

Native HIV-1 Proteinase

Summary for 1ODW
Entry DOI10.2210/pdb1odw/pdb
Related1ODX
DescriptorHIV-1 PROTEASE, di-tert-butyl {iminobis[(2S,3S)-3-hydroxy-1-phenylbutane-4,2-diyl]}biscarbamate (3 entities in total)
Functional Keywordsproteinase, retropepsin, retrovirus, hiv, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHuman immunodeficiency virus 1 (HIV-1)
Cellular locationMatrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P04585
Total number of polymer chains2
Total formula weight22123.15
Authors
Thanki, N.,Kervinen, J.,Wlodawer, A. (deposition date: 1996-09-16, release date: 1997-04-01, Last modification date: 2024-02-14)
Primary citationKervinen, J.,Thanki, N.,Zdanov, A.,Tino, J.,Barrish, J.,Lin, P.F.,Colonno, R.,Riccardi, K.,Samanta, H.,Wlodawer, A.
Structural Analysis of the Native and Drug-Resistant HIV-1 Proteinases Complexed with an Aminodiol Inhibitor
Protein Pept.Lett., 3:399-, 1996
Cited by
Experimental method
X-RAY DIFFRACTION (2.1 Å)
Structure validation

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