1O1S
Structure of FPT bound to isoprenoid analog 3b
Summary for 1O1S
Entry DOI | 10.2210/pdb1o1s/pdb |
Related | 1QBQ |
Descriptor | Protein farnesyltransferase alpha subunit, Protein farnesyltransferase beta subunit, ZINC ION, ... (5 entities in total) |
Functional Keywords | transferase, prenyltransferase |
Biological source | Rattus norvegicus (Norway rat) More |
Total number of polymer chains | 2 |
Total formula weight | 92707.54 |
Authors | Turek-Etienne, T.C.,Strickland, C.L.,Distefano, M.D. (deposition date: 2003-01-14, release date: 2003-05-06, Last modification date: 2024-03-13) |
Primary citation | Turek-Etienne, T.C.,Strickland, C.L.,Distefano, M.D. Biochemical and Structural Studies with Prenyl Diphosphate Analogues Provide Insights into Isoprenoid Recognition by Protein Farnesyl Transferase Biochemistry, 42:3716-3724, 2003 Cited by PubMed: 12667062DOI: 10.1021/bi0266838 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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