1O0O

Ribonuclease A in complex with adenosine-2',5'-diphosphate

Summary for 1O0O

• Entry DOI: 10.2210/pdb1o0o/pdb
• Related: 1O0F 1O0H 1O0M 1O0N
• Descriptor: Ribonuclease pancreatic, ADENOSINE-2'-5'-DIPHOSPHATE (3 entities in total)
• Functional Keywords: hydrolase, ribonuclease
• Biological source: Bos taurus (cattle)
• Cellular location: Secreted: P61823
• Total number of polymer chains: 2
• Total formula weight: 28271.05

Authors

Leonidas, D.D.,Oikonomakos, N.G.,Chrysina, E.D.,Kosmopoulou, M.N.,Vlassi, M. (deposition date: 2003-02-24, release date: 2003-12-09, Last modification date: 2023-10-25)

• Primary citation: Leonidas, D.D.,Chavali, G.B.,Oikonomakos, N.G.,Chrysina, E.D.,Kosmopoulou, M.N.,Vlassi, M.,Frankling, C.,Acharya, K.R.; High-resolution crystal structures of ribonuclease A complexed with adenylic and uridylic nucleotide inhibitors. Implications for structure-based design of ribonucleolytic inhibitors; PROTEIN SCI., 12:2559-2574, 2003; PubMed: 14573867; DOI: 10.1110/ps.03196603

Experimental method

X-RAY DIFFRACTION (1.2 Å)