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1NZQ

D-Phe-Pro-Arg-Type Thrombin Inhibitor

Summary for 1NZQ
Entry DOI10.2210/pdb1nzq/pdb
Related1A5G 1O0D 1PPB
Related PRD IDPRD_000480
DescriptorThrombin light chain, Thrombin heavy chain, Decapeptide Hirudin Analogue, ... (5 entities in total)
Functional Keywordsthrombin, thrombin inhibitor, blood clotting, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHomo sapiens (human)
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Cellular locationSecreted, extracellular space: P00734 P00734
Total number of polymer chains3
Total formula weight35847.90
Authors
Lange, U.E.,Bauke, D.,Hornberger, W.,Mack, H.,Seitz, W.,Hoeffken, H.W. (deposition date: 2003-02-19, release date: 2003-10-14, Last modification date: 2018-04-04)
Primary citationLange, U.E.,Bauke, D.,Hornberger, W.,Mack, H.,Seitz, W.,Hoeffken, H.W.
D-Phe-Pro-Arg type thrombin inhibitors: unexpected selectivity by modification of the P1 moiety
Bioorg.Med.Chem.Lett., 13:2029-2033, 2003
Cited by
PubMed: 12781189
DOI: 10.1016/S0960-894X(03)00236-1
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.18 Å)
Structure validation

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