1N2V
Crystal Structure of TGT in complex with 2-Butyl-5,6-dihydro-1H-imidazo[4,5-d]pyridazine-4,7-dione
Summary for 1N2V
Entry DOI | 10.2210/pdb1n2v/pdb |
Related | 1ENU 1PUD |
Descriptor | Queuine tRNA-ribosyltransferase, ZINC ION, 2-BUTYL-5,6-DIHYDRO-1H-IMIDAZO[4,5-D]PYRIDAZINE-4,7-DIONE, ... (4 entities in total) |
Functional Keywords | protein-ligand complex, transferase |
Biological source | Zymomonas mobilis |
Total number of polymer chains | 1 |
Total formula weight | 43199.33 |
Authors | Brenk, R.,Naerum, L.,Graedler, U.,Gerber, H.-D.,Garcia, G.A.,Reuter, K.,Stubbs, M.T.,Klebe, G. (deposition date: 2002-10-24, release date: 2003-04-08, Last modification date: 2024-02-14) |
Primary citation | Brenk, R.,Naerum, L.,Graedler, U.,Gerber, H.-D.,Garcia, G.A.,Reuter, K.,Stubbs, M.T.,Klebe, G. Virtual screening for submicromolar leads of tRNA-guanine transglycosylase based on a new unexpected binding mode detected by crystal structure analysis J.Med.Chem., 46:1133-1143, 2003 Cited by PubMed: 12646024DOI: 10.1021/jm0209937 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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