1MMK

Crystal structure of ternary complex of the catalytic domain of human phenylalanine hydroxylase ((FeII)) complexed with tetrahydrobiopterin and thienylalanine

Summary for 1MMK

Entry DOI	10.2210/pdb1mmk/pdb
Related	1J8T 1J8U 1KW0 1MMT
Descriptor	Phenylalanine-4-hydroxylase, FE (II) ION, SULFATE ION, ... (6 entities in total)
Functional Keywords	basket-arrangement, 13 alpha-helices, 8 beta-strands, ferrous iron, oxidoreductase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	38165.94
Authors	Andersen, O.A.,Flatmark, T.,Hough, E. (deposition date: 2002-09-04, release date: 2003-09-04, Last modification date: 2023-10-25)
Primary citation	Andersen, O.A.,Stokka, A.J.,Flatmark, T.,Hough, E. 2.0A resolution crystal structures of the ternary complexes of human phenylalanine hydroxylase catalytic domain with tetrahydrobiopterin and 3-(2-thienyl)-L-alanine or L-norleucine: substrate specificity and molecular motions related to substrate binding J.Mol.Biol., 333:747-757, 2003 Cited by PubMed: 14568534 DOI: 10.1016/j.jmb.2003.09.004 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation