1J8U

Catalytic Domain of Human Phenylalanine Hydroxylase Fe(II) in Complex with Tetrahydrobiopterin

Summary for 1J8U

Entry DOI	10.2210/pdb1j8u/pdb
Related	1J8T
Descriptor	PHENYLALANINE-4-HYDROXYLASE, FE (II) ION, 5,6,7,8-TETRAHYDROBIOPTERIN, ... (4 entities in total)
Functional Keywords	ferrous iron, 2-his-1-carboxylate facial triad, tetrahydrobiopterin, oxidoreductase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	37898.66
Authors	Andersen, O.A.,Flatmark, T.,Hough, E. (deposition date: 2001-05-22, release date: 2002-05-22, Last modification date: 2023-08-16)
Primary citation	Andersen, O.A.,Flatmark, T.,Hough, E. High resolution crystal structures of the catalytic domain of human phenylalanine hydroxylase in its catalytically active Fe(II) form and binary complex with tetrahydrobiopterin. J.Mol.Biol., 314:279-291, 2001 Cited by PubMed: 11718561 DOI: 10.1006/jmbi.2001.5061 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation