1LEW

CRYSTAL STRUCTURE OF MAP KINASE P38 COMPLEXED TO THE DOCKING SITE ON ITS NUCLEAR SUBSTRATE MEF2A

Summary for 1LEW

• Entry DOI: 10.2210/pdb1lew/pdb
• Related: 1LEZ
• Descriptor: Mitogen-activated protein kinase 14, Myocyte-specific enhancer factor 2A (3 entities in total)
• Functional Keywords: protein-peptide complex, transferase, map kinase, serine/threonine-protein kinase, p38, mef2a
• Biological source: Mus musculus (Mouse); More
• Cellular location: Cytoplasm : P47811; Nucleus : Q02078
• Total number of polymer chains: 2
• Total formula weight: 42717.83

Authors

Chang, C.-I.,Xu, B.-E.,Akella, R.,Cobb, M.H.,Goldsmith, E.J. (deposition date: 2002-04-10, release date: 2002-07-10, Last modification date: 2024-02-14)

• Primary citation: Chang, C.I.,Xu, B.E.,Akella, R.,Cobb, M.H.,Goldsmith, E.J.; Crystal structures of MAP kinase p38 complexed to the docking sites on its nuclear substrate MEF2A and activator MKK3b.; Mol.Cell, 9:1241-1249, 2002; PubMed: 12086621; DOI: 10.1016/S1097-2765(02)00525-7

Experimental method

X-RAY DIFFRACTION (2.3 Å)