1LEW
CRYSTAL STRUCTURE OF MAP KINASE P38 COMPLEXED TO THE DOCKING SITE ON ITS NUCLEAR SUBSTRATE MEF2A
Summary for 1LEW
Entry DOI | 10.2210/pdb1lew/pdb |
Related | 1LEZ |
Descriptor | Mitogen-activated protein kinase 14, Myocyte-specific enhancer factor 2A (3 entities in total) |
Functional Keywords | protein-peptide complex, transferase, map kinase, serine/threonine-protein kinase, p38, mef2a |
Biological source | Mus musculus (Mouse) More |
Cellular location | Cytoplasm : P47811 Nucleus : Q02078 |
Total number of polymer chains | 2 |
Total formula weight | 42717.83 |
Authors | Chang, C.-I.,Xu, B.-E.,Akella, R.,Cobb, M.H.,Goldsmith, E.J. (deposition date: 2002-04-10, release date: 2002-07-10, Last modification date: 2024-02-14) |
Primary citation | Chang, C.I.,Xu, B.E.,Akella, R.,Cobb, M.H.,Goldsmith, E.J. Crystal structures of MAP kinase p38 complexed to the docking sites on its nuclear substrate MEF2A and activator MKK3b. Mol.Cell, 9:1241-1249, 2002 Cited by PubMed: 12086621DOI: 10.1016/S1097-2765(02)00525-7 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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