1LE4

STRUCTURAL BASIS FOR ALTERED FUNCTION IN THE COMMON MUTANTS OF HUMAN APOLIPOPROTEIN-E

Summary for 1LE4

• Entry DOI: 10.2210/pdb1le4/pdb
• Descriptor: APOLIPOPROTEIN E4 (2 entities in total)
• Functional Keywords: lipoprotein
• Biological source: Homo sapiens (human)
• Cellular location: Secreted: P02649
• Total number of polymer chains: 1
• Total formula weight: 16797.13

Authors

Wilson, C.,Agard, D.A. (deposition date: 1991-08-22, release date: 1992-10-15, Last modification date: 2024-02-14)

• Primary citation: Dong, L.M.,Wilson, C.,Wardell, M.R.,Simmons, T.,Mahley, R.W.,Weisgraber, K.H.,Agard, D.A.; Human apolipoprotein E. Role of arginine 61 in mediating the lipoprotein preferences of the E3 and E4 isoforms.; J.Biol.Chem., 269:22358-22365, 1994; PubMed: 8071364

Experimental method

X-RAY DIFFRACTION (2.5 Å)