1LDT
COMPLEX OF LEECH-DERIVED TRYPTASE INHIBITOR WITH PORCINE TRYPSIN
Summary for 1LDT
Entry DOI | 10.2210/pdb1ldt/pdb |
Descriptor | TRYPSIN, TRYPTASE INHIBITOR, CALCIUM ION, ... (4 entities in total) |
Functional Keywords | complex (hydrolase-inhibitor), hydrolase, inhibitor, inflammation, tryptase, complex (hydrolase-inhibitor) complex, complex (hydrolase/inhibitor) |
Biological source | Hirudo medicinalis (medicinal leech) More |
Cellular location | Secreted, extracellular space: P00761 |
Total number of polymer chains | 2 |
Total formula weight | 28284.19 |
Authors | Stubbs, M.T. (deposition date: 1997-05-15, release date: 1998-05-20, Last modification date: 2024-04-03) |
Primary citation | Stubbs, M.T.,Morenweiser, R.,Sturzebecher, J.,Bauer, M.,Bode, W.,Huber, R.,Piechottka, G.P.,Matschiner, G.,Sommerhoff, C.P.,Fritz, H.,Auerswald, E.A. The three-dimensional structure of recombinant leech-derived tryptase inhibitor in complex with trypsin. Implications for the structure of human mast cell tryptase and its inhibition. J.Biol.Chem., 272:19931-19937, 1997 Cited by PubMed: 9242660DOI: 10.1074/jbc.272.32.19931 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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