1KJL

High Resolution X-Ray Structure of Human Galectin-3 in complex with LacNAc

Summary for 1KJL

Entry DOI	10.2210/pdb1kjl/pdb
Related	1A3K 1KJR
Descriptor	Galectin-3, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... (5 entities in total)
Functional Keywords	lacnac complex, sugar binding protein
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	16950.38
Authors	Sorme, P.,Arnoux, P.,Kahl-Knutsson, B.,Leffler, H.,Rini, J.M.,Nilsson, U.J. (deposition date: 2001-12-04, release date: 2005-04-12, Last modification date: 2023-08-16)
Primary citation	Sorme, P.,Arnoux, P.,Kahl-Knutsson, B.,Leffler, H.,Rini, J.M.,Nilsson, U.J. Structural and thermodynamic studies on cation-Pi interactions in lectin-ligand complexes: high-affinity galectin-3 inhibitors through fine-tuning of an arginine-arene interaction. J.Am.Chem.Soc., 127:1737-1743, 2005 Cited by PubMed: 15701008 DOI: 10.1021/ja043475p PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.4 Å)

Structure validation