1KA6

SAP/SH2D1A bound to peptide n-pY

Summary for 1KA6

• Entry DOI: 10.2210/pdb1ka6/pdb
• Related: 1KA7
• NMR Information: BMRB: 5212
• Descriptor: SH2 DOMAIN PROTEIN 1A, peptide n-pY (2 entities in total)
• Functional Keywords: sh2 domain, protein-peptide complex, immune system
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm (Probable): O60880; Cell membrane; Single-pass type I membrane protein: Q13291
• Total number of polymer chains: 2
• Total formula weight: 15237.31

Authors

Hwang, P.M.,Li, C.,Morra, M.,Lillywhite, J.,Gertler, F.,Terhorst, C.,Kay, L.E.,Pawson, T.,Forman-Kay, J.,Li, S.-C. (deposition date: 2001-10-31, release date: 2001-11-07, Last modification date: 2021-10-27)

• Primary citation: Hwang, P.M.,Li, C.,Morra, M.,Lillywhite, J.,Muhandiram, D.R.,Gertler, F.,Terhorst, C.,Kay, L.E.,Pawson, T.,Forman-Kay, J.D.,Li, S.C.; A "three-pronged" binding mechanism for the SAP/SH2D1A SH2 domain: structural basis and relevance to the XLP syndrome.; EMBO J., 21:314-323, 2002; PubMed: 11823424; DOI: 10.1093/emboj/21.3.314

Experimental method

SOLUTION NMR