1K3T
Structure of Glycosomal Glyceraldehyde-3-Phosphate Dehydrogenase from Trypanosoma cruzi Complexed with Chalepin, a Coumarin Derivative Inhibitor
Summary for 1K3T
Entry DOI | 10.2210/pdb1k3t/pdb |
Descriptor | Glyceraldehyde-3-phosphate dehydrogenase, 6-(1,1-DIMETHYLALLYL)-2-(1-HYDROXY-1-METHYLETHYL)-2,3-DIHYDRO-7H-FURO[3,2-G]CHROMEN-7-ONE (3 entities in total) |
Functional Keywords | apo-protein, ggapdh-chalepin complex, glycosome, trypanosoma cruzi, oxidoreductase |
Biological source | Trypanosoma cruzi |
Cellular location | Glycosome: P22513 |
Total number of polymer chains | 4 |
Total formula weight | 156764.53 |
Authors | Pavao, F. (deposition date: 2001-10-04, release date: 2002-06-19, Last modification date: 2024-04-03) |
Primary citation | Pavao, F.,Castilho, M.S.,Pupo, M.T.,Dias, R.L.,Correa, A.G.,Fernandes, J.B.,da Silva, M.F.,Mafezoli, J.,Vieira, P.C.,Oliva, G. Structure of Trypanosoma cruzi glycosomal glyceraldehyde-3-phosphate dehydrogenase complexed with chalepin, a natural product inhibitor, at 1.95 A resolution. FEBS Lett., 520:13-17, 2002 Cited by PubMed: 12044862DOI: 10.1016/S0014-5793(02)02700-X PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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