1JLX

AGGLUTININ IN COMPLEX WITH T-DISACCHARIDE

Summary for 1JLX

• Entry DOI: 10.2210/pdb1jlx/pdb
• Related: 1JLY
• Related PRD ID: PRD_900084
• Descriptor: AGGLUTININ, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-alpha-D-galactopyranose, FORMYL GROUP, ... (5 entities in total)
• Functional Keywords: complex (lectin-saccharide), t-disaccharide homodimer, bivalent, lectin
• Biological source: Amaranthus caudatus (amaranth)
• Total number of polymer chains: 2
• Total formula weight: 70635.67

Authors

Transue, T.R.,Smith, A.K.,Mo, H.,Goldstein, I.J.,Saper, M.A. (deposition date: 1997-07-23, release date: 1997-12-03, Last modification date: 2023-08-09)

Primary citation

Transue, T.R.,Smith, A.K.,Mo, H.,Goldstein, I.J.,Saper, M.A.
Structure of benzyl T-antigen disaccharide bound to Amaranthus caudatus agglutinin.
Nat.Struct.Biol., 4:779-783, 1997

PubMed Abstract: Amaranthus caudatus agglutinin contains a novel arrangement of four beta-trefoil domains. The sugar-binding site provides specificity for the carcinoma-associated T-antigen disaccharide even when 'masked' by other sugars.

PubMed: 9334739
DOI: 10.1038/nsb1097-779

Experimental method

X-RAY DIFFRACTION (2.2 Å)