1JJE

IMP-1 METALLO BETA-LACTAMASE FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH A BIARYL SUCCINIC ACID INHIBITOR (11)

Summary for 1JJE

• Entry DOI: 10.2210/pdb1jje/pdb
• Related: 1JJT
• Descriptor: IMP-1 METALLO BETA-LACTAMASE, ZINC ION, ACETATE ION, ... (5 entities in total)
• Functional Keywords: metallo-beta-lactamase inhibitor, succinic acid inhibitor, imp-1 metallo-beta-lactamase, hydrolase
• Biological source: Pseudomonas aeruginosa
• Cellular location: Periplasm : P52699
• Total number of polymer chains: 2
• Total formula weight: 50265.24

Authors

Fitzgerald, P.M.D.,Sharma, N. (deposition date: 2001-07-04, release date: 2001-07-25, Last modification date: 2024-04-03)

• Primary citation: Toney, J.H.,Hammond, G.G.,Fitzgerald, P.M.,Sharma, N.,Balkovec, J.M.,Rouen, G.P.,Olson, S.H.,Hammond, M.L.,Greenlee, M.L.,Gao, Y.D.; Succinic acids as potent inhibitors of plasmid-borne IMP-1 metallo-beta-lactamase.; J.Biol.Chem., 276:31913-31918, 2001; PubMed: 11390410; DOI: 10.1074/jbc.M104742200

Experimental method

X-RAY DIFFRACTION (1.8 Å)