Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0008800 | molecular_function | beta-lactamase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0017001 | biological_process | antibiotic catabolic process |
| A | 0042597 | cellular_component | periplasmic space |
| A | 0046677 | biological_process | response to antibiotic |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0008800 | molecular_function | beta-lactamase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0017001 | biological_process | antibiotic catabolic process |
| B | 0042597 | cellular_component | periplasmic space |
| B | 0046677 | biological_process | response to antibiotic |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 251 |
| Chain | Residue |
| A | HIS77 |
| A | HIS79 |
| A | HIS139 |
| A | BYS250 |
| A | ZN252 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 252 |
| Chain | Residue |
| A | ZN251 |
| A | ASP81 |
| A | CYS158 |
| A | HIS197 |
| A | BYS250 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ACT A 260 |
| Chain | Residue |
| A | LYS8 |
| A | THR20 |
| A | PHE22 |
| A | PRO32 |
| A | HIS34 |
| A | GLU199 |
| A | ZN261 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 261 |
| Chain | Residue |
| A | HIS34 |
| A | GLU199 |
| A | ACT260 |
| A | HOH1031 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN B 251 |
| Chain | Residue |
| B | HIS77 |
| B | HIS79 |
| B | HIS139 |
| B | BYS250 |
| B | ZN252 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN B 252 |
| Chain | Residue |
| B | ASP81 |
| B | CYS158 |
| B | HIS197 |
| B | BYS250 |
| B | ZN251 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT B 260 |
| Chain | Residue |
| B | LYS8 |
| B | HIS34 |
| B | GLU199 |
| B | ZN261 |
| B | HOH1019 |
| B | HOH1044 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 261 |
| Chain | Residue |
| B | HIS34 |
| B | GLU199 |
| B | ACT260 |
| B | HOH1019 |
| site_id | AC9 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE BYS A 250 |
| Chain | Residue |
| A | TRP28 |
| A | HIS77 |
| A | HIS79 |
| A | SER80 |
| A | ASP81 |
| A | HIS139 |
| A | CYS158 |
| A | LYS161 |
| A | GLY166 |
| A | ASN167 |
| A | HIS197 |
| A | ZN251 |
| A | ZN252 |
| site_id | BC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE BYS B 250 |
| Chain | Residue |
| B | TRP28 |
| B | PHE51 |
| B | HIS77 |
| B | HIS79 |
| B | SER80 |
| B | ASP81 |
| B | HIS139 |
| B | CYS158 |
| B | LYS161 |
| B | GLY164 |
| B | GLY166 |
| B | ASN167 |
| B | HIS197 |
| B | ZN251 |
| B | ZN252 |
Functional Information from PROSITE/UniProt
| site_id | PS00743 |
| Number of Residues | 20 |
| Details | BETA_LACTAMASE_B_1 Beta-lactamases class B signature 1. IsSHfHSDstGGiewlnsr.S |
| Chain | Residue | Details |
| A | ILE74-SER93 | |
| site_id | PS00744 |
| Number of Residues | 13 |
| Details | BETA_LACTAMASE_B_2 Beta-lactamases class B signature 2. PerkILfGgCFIK |
| Chain | Residue | Details |
| A | PRO149-LYS161 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"26482303","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P25910","evidenceCode":"ECO:0000250"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 2bmi |
| Chain | Residue | Details |
| A | ASP81 | |
| A | ASN167 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 2bmi |
| Chain | Residue | Details |
| B | ASP81 | |
| B | ASN167 | |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 2bmi |
| Chain | Residue | Details |
| A | ASP81 | |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 2bmi |
| Chain | Residue | Details |
| B | ASP81 | |
