1J73
Crystal structure of an unstable insulin analog with native activity.
Summary for 1J73
Entry DOI | 10.2210/pdb1j73/pdb |
Related | 1TRZ |
Descriptor | insulin a, insulin b, ZINC ION, ... (4 entities in total) |
Functional Keywords | a8-diaminobutyric acid human insulin, hormone-receptor interface, hormone-growth factor complex, hormone/growth factor |
Cellular location | Secreted: P01308 P01308 |
Total number of polymer chains | 4 |
Total formula weight | 11764.15 |
Authors | Wan, Z.,Zhao, M.,Nakagawa, S.,Jia, W.,Weiss, M.A. (deposition date: 2001-05-15, release date: 2001-05-30, Last modification date: 2021-10-27) |
Primary citation | Weiss, M.A.,Wan, Z.,Zhao, M.,Chu, Y.C.,Nakagawa, S.H.,Burke, G.T.,Jia, W.,Hellmich, R.,Katsoyannis, P.G. Non-standard insulin design: structure-activity relationships at the periphery of the insulin receptor. J.Mol.Biol., 315:103-111, 2002 Cited by PubMed: 11779231DOI: 10.1006/jmbi.2001.5224 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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