1IH0
Structure of the C-domain of Human Cardiac Troponin C in Complex with Ca2+ Sensitizer EMD 57033
Summary for 1IH0
Entry DOI | 10.2210/pdb1ih0/pdb |
Related | 1AJ4 |
NMR Information | BMRB: 4994 |
Descriptor | TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES, CALCIUM ION, 5-[1-(3,4-DIMETHOXY-BENZOYL)-1,2,3,4-TETRAHYDRO-QUINOLIN-6-YL]-6-METHYL-3,6-DIHYDRO-[1,3,4]THIADIAZIN-2-ONE (3 entities in total) |
Functional Keywords | ca2+ binding protein, ca2+ sensitizer, contractile protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 8757.69 |
Authors | Wang, X.,Li, M.X.,Spyracopoulos, L.,Beier, N.,Chandra, M.,Solaro, R.J.,Sykes, B.D. (deposition date: 2001-04-18, release date: 2001-10-10, Last modification date: 2024-05-22) |
Primary citation | Wang, X.,Li, M.X.,Spyracopoulos, L.,Beier, N.,Chandra, M.,Solaro, R.J.,Sykes, B.D. Structure of the C-domain of human cardiac troponin C in complex with the Ca2+ sensitizing drug EMD 57033. J.Biol.Chem., 276:25456-25466, 2001 Cited by PubMed: 11320096DOI: 10.1074/jbc.M102418200 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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