1I4M

Crystal structure of the human prion protein reveals a mechanism for oligomerization

Summary for 1I4M

Entry DOI	10.2210/pdb1i4m/pdb
Descriptor	MAJOR PRION PROTEIN, CADMIUM ION, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	domain-swapped dimer, membrane protein
Biological source	Homo sapiens (human)
Cellular location	Cell membrane; Lipid-anchor, GPI-anchor. Isoform 2: Cytoplasm: P04156
Total number of polymer chains	1
Total formula weight	12975.42
Authors	Knaus, K.J.,Morillas, M.,Swietnicki, W.,Malone, M.,Surewicz, W.K.,Yee, V.C. (deposition date: 2001-02-22, release date: 2002-02-27, Last modification date: 2011-07-13)
Primary citation	Knaus, K.J.,Morillas, M.,Swietnicki, W.,Malone, M.,Surewicz, W.K.,Yee, V.C. Crystal structure of the human prion protein reveals a mechanism for oligomerization. Nat.Struct.Biol., 8:770-774, 2001 Cited by PubMed: 11524679 DOI: 10.1038/nsb0901-770 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation