1HR2

CRYSTAL STRUCTURE ANALYSIS OF A MUTANT P4-P6 DOMAIN (DELC209) OF TETRAHYMENA THEMOPHILA GROUP I INTRON.

Summary for 1HR2

Entry DOI	10.2210/pdb1hr2/pdb
Related	1gid
Descriptor	P4-P6 DELC209 MUTANT RNA RIBOZYME DOMAIN, MAGNESIUM ION (3 entities in total)
Functional Keywords	rna, p4-p6, c209, ribozyme, tetrahymena, group i intron, ribonucleic acid
Total number of polymer chains	2
Total formula weight	103203.51
Authors	Juneau, K.,Podell, E.R.,Harrington, D.J.,Cech, T.R. (deposition date: 2000-12-20, release date: 2001-04-12, Last modification date: 2023-08-09)
Primary citation	Juneau, K.,Podell, E.,Harrington, D.J.,Cech, T.R. Structural basis of the enhanced stability of a mutant ribozyme domain and a detailed view of RNA--solvent interactions. Structure, 9:221-231, 2001 Cited by PubMed Abstract: The structure of P4-P6, a 160 nucleotide domain of the self-splicing Tetrahymena thermophila intron, was solved previously. Mutants of the P4-P6 RNA that form a more stable tertiary structure in solution were recently isolated by successive rounds of in vitro selection and amplification. PubMed: 11286889 DOI: 10.1016/S0969-2126(01)00579-2 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation