1HOV
SOLUTION STRUCTURE OF A CATALYTIC DOMAIN OF MMP-2 COMPLEXED WITH SC-74020
Summary for 1HOV
Entry DOI | 10.2210/pdb1hov/pdb |
Descriptor | MATRIX METALLOPROTEINASE-2, ZINC ION, CALCIUM ION, ... (4 entities in total) |
Functional Keywords | enzyme-inhibitor complex, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Secreted, extracellular space, extracellular matrix: P08253 |
Total number of polymer chains | 1 |
Total formula weight | 19277.10 |
Authors | Feng, Y.,Likos, J.J.,Zhu, L.,Woodward, H.,Munie, G.,McDonald, J.J.,Stevens, A.M.,Howard, C.P.,De Crescenzo, G.A.,Welsch, D.,Shieh, H.-S.,Stallings, W.C. (deposition date: 2000-12-11, release date: 2001-12-12, Last modification date: 2024-05-22) |
Primary citation | Feng, Y.,Likos, J.J.,Zhu, L.,Woodward, H.,Munie, G.,McDonald, J.J.,Stevens, A.M.,Howard, C.P.,De Crescenzo, G.A.,Welsch, D.,Shieh, H.-S.,Stallings, W.C. Solution structure and backbone dynamics of the catalytic domain of matrix metalloproteinase-2 complexed with a hydroxamic acid inhibitor Biochim.Biophys.Acta, 1598:10-23, 2002 Cited by PubMed: 12147339DOI: 10.1016/S0167-4838(02)00307-2 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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