1GZL

Crystal structure of C14linkmid/IQN17: a cross-linked inhibitor of HIV-1 entry bound to the gp41 hydrophobic pocket

Summary for 1GZL

Entry DOI	10.2210/pdb1gzl/pdb
Related	1DGC 1E7T 1ENV 1FAV 1GCL 1GCM 1GK6 1IHQ 1IJ0 1IJ1 1IJ2 1IJ3 1KQL 1PIQ 1SWI 1TMZ 1YSA 1ZII 1ZIJ 1ZIK 1ZIL 1ZIM 1ZTA 2DGC 2ZTA
Descriptor	FUSION PROTEIN BETWEEN THE HYDROPHOBIC POCKET OF HIV GP41 AND GENERAL CONTROL PROTEIN GCN4-PIQI, ENVELOPE GLYCOPROTEIN GP41, CHLORIDE ION, ... (5 entities in total)
Functional Keywords	glycoprotein, hiv entry, inhibitor, cross-link, gp41, coiled coil
Biological source	SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) More
Total number of polymer chains	4
Total formula weight	14553.81
Authors	Sia, S.K.,Carr, P.A.,Cochran, A.G.,Malashkevich, V.M.,Kim, P.S. (deposition date: 2002-05-23, release date: 2002-10-10, Last modification date: 2019-11-20)
Primary citation	Sia, S.K.,Carr, P.A.,Cochran, A.G.,Malashkevich, V.M.,Kim, P.S. Short Constrained Peptides that Inhibit HIV-1 Entry Proc.Natl.Acad.Sci.USA, 99:14664-, 2002 Cited by PubMed: 12417739 DOI: 10.1073/PNAS.232566599 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation