1GG6
CRYSTAL STRUCTURE OF GAMMA CHYMOTRYPSIN WITH N-ACETYL-PHENYLALANINE TRIFLUOROMETHYL KETONE BOUND AT THE ACTIVE SITE
Summary for 1GG6
Entry DOI | 10.2210/pdb1gg6/pdb |
Related | 1GGD 2GCH 6GCH 7GCH |
Descriptor | GAMMA CHYMOTRYPSIN, SULFATE ION, N-(1-BENZYL-3,3,3-TRIFLUORO-2,2-DIHYDROXY-PROPYL)-ACETAMIDE, ... (8 entities in total) |
Functional Keywords | chymotrypsin, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Bos taurus (cattle) More |
Cellular location | Secreted, extracellular space: P00766 P00766 P00766 |
Total number of polymer chains | 3 |
Total formula weight | 26078.20 |
Authors | Neidhart, D.,Wei, Y.,Cassidy, C.,Lin, J.,Cleland, W.W.,Frey, P.A. (deposition date: 2000-07-31, release date: 2000-09-20, Last modification date: 2023-12-27) |
Primary citation | Neidhart, D.,Wei, Y.,Cassidy, C.,Lin, J.,Cleland, W.W.,Frey, P.A. Correlation of low-barrier hydrogen bonding and oxyanion binding in transition state analogue complexes of chymotrypsin. Biochemistry, 40:2439-2447, 2001 Cited by PubMed: 11327865DOI: 10.1021/bi002535a PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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