Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0004252 | molecular_function | serine-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| C | 0004252 | molecular_function | serine-type endopeptidase activity |
| C | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 B 305 |
| Chain | Residue |
| B | LYS36 |
| B | SER92 |
| B | HOH408 |
| B | HOH422 |
| B | HOH564 |
| C | TRP237 |
| C | HOH559 |
| C | HOH680 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 C 306 |
| Chain | Residue |
| C | PRO152 |
| C | ASP153 |
| C | ARG154 |
| C | HOH553 |
| B | HOH470 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 C 307 |
| Chain | Residue |
| B | PHE130 |
| C | LEU162 |
| C | LEU163 |
| C | ARG230 |
| C | HOH719 |
| site_id | AC4 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE APF C 301 |
| Chain | Residue |
| B | HIS57 |
| B | LEU97 |
| B | EDO313 |
| B | HOH626 |
| C | SER190 |
| C | CYS191 |
| C | MET192 |
| C | GLY193 |
| C | ASP194 |
| C | SER195 |
| C | SER214 |
| C | TRP215 |
| C | GLY216 |
| C | SER217 |
| C | HOH702 |
| site_id | AC5 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE APL B 302 |
| Chain | Residue |
| B | GLN34 |
| B | GLY38 |
| B | VAL67 |
| B | GLU70 |
| B | GLN73 |
| B | SER75 |
| B | SER76 |
| B | ILE80 |
| B | LYS82 |
| B | PRO124 |
| B | SER125 |
| B | EDO311 |
| B | HOH495 |
| B | HOH511 |
| B | HOH699 |
| C | GLN239 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO C 310 |
| Chain | Residue |
| B | ILE99 |
| B | EDO313 |
| B | HOH732 |
| C | LYS175 |
| C | TRP215 |
| C | HOH427 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 311 |
| Chain | Residue |
| B | LYS36 |
| B | GLY38 |
| B | LYS82 |
| B | APL302 |
| B | HOH487 |
| B | HOH506 |
| C | HOH671 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO C 312 |
| Chain | Residue |
| B | ILE47 |
| B | ASN48 |
| C | GLN239 |
| C | HOH708 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 313 |
| Chain | Residue |
| B | SER96 |
| B | LEU97 |
| B | ILE99 |
| B | HOH695 |
| B | HOH732 |
| C | APF301 |
| C | EDO310 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VTAAHC |
| Chain | Residue | Details |
| B | VAL53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. SScmGDSGGPLV |
| Chain | Residue | Details |
| C | SER189-VAL200 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Charge relay system |
| Chain | Residue | Details |
| C | SER195 | |
| B | ASP102 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1hja |
| Chain | Residue | Details |
| C | SER195 | |
| C | GLY193 | |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1hja |
| Chain | Residue | Details |
| C | SER195 | |
| C | GLY196 | |
| B | ASP102 | |
| B | HIS57 | |
| site_id | MCSA1 |
| Number of Residues | 3 |
| Details | M-CSA 387 |
| Chain | Residue | Details |
| C | GLY193 | electrostatic stabiliser |
| C | SER195 | covalent catalysis |
| C | GLY196 | electrostatic stabiliser |
