1GC1

HIV-1 GP120 CORE COMPLEXED WITH CD4 AND A NEUTRALIZING HUMAN ANTIBODY

Summary for 1GC1

Entry DOI	10.2210/pdb1gc1/pdb
Descriptor	ENVELOPE PROTEIN GP120, CD4, ANTIBODY 17B, ... (7 entities in total)
Functional Keywords	complex (hiv envelope protein-cd4-fab), hiv-1 exterior envelope gp120, t-cell surface glycoprotein cd4, antigen-binding fragment of human immunoglobulin 17b, glycosylated protein, viral protein-receptor-immune system complex, viral protein/receptor/immune system
Biological source	Human immunodeficiency virus 1 More
Total number of polymer chains	4
Total formula weight	106802.56
Authors	Kwong, P.D.,Wyatt, R.,Robinson, J.,Sweet, R.W.,Sodroski, J.,Hendrickson, W.A. (deposition date: 1998-06-15, release date: 1998-07-08, Last modification date: 2023-08-09)
Primary citation	Kwong, P.D.,Wyatt, R.,Robinson, J.,Sweet, R.W.,Sodroski, J.,Hendrickson, W.A. Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody. Nature, 393:648-659, 1998 Cited by PubMed: 9641677 DOI: 10.1038/31405 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation