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1G0E

SITE-SPECIFIC MUTANT (HIS64 REPLACED WITH ALA) OF HUMAN CARBONIC ANHYDRASE II COMPLEXED WITH 4-METHYLIMIDAZOLE

Summary for 1G0E
Entry DOI10.2210/pdb1g0e/pdb
Related1G0F
DescriptorCARBONIC ANHYDRASE II, ZINC ION, MERCURY (II) ION, ... (5 entities in total)
Functional Keywordstwisted beta sheet, chemical rescue, 4-methylimidazole, zinc metalloenzyme, protein ligand complex, lyase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm : P00918
Total number of polymer chains1
Total formula weight29570.09
Authors
Duda, D.,McKenna, R. (deposition date: 2000-10-06, release date: 2000-10-18, Last modification date: 2024-02-07)
Primary citationDuda, D.,Tu, C.,Qian, M.,Laipis, P.,Agbandje-McKenna, M.,Silverman, D.N.,McKenna, R.
Structural and kinetic analysis of the chemical rescue of the proton transfer function of carbonic anhydrase II.
Biochemistry, 40:1741-1748, 2001
Cited by
PubMed: 11327835
DOI: 10.1021/bi002295z
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.6 Å)
Structure validation

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