1FSG
TOXOPLASMA GONDII HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE COMPLEXED WITH 9-DEAZAGUANINE, ALPHA-D-5-PHOSPHORIBOSYL-1-PYROPHOSPHATE (PRPP) AND TWO MG2+ IONS
Summary for 1FSG
Entry DOI | 10.2210/pdb1fsg/pdb |
Related | 1BZY 1DBR 1HMP 1QK3 1QK4 1QK5 1TC2 |
Descriptor | HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE, MAGNESIUM ION, 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, ... (5 entities in total) |
Functional Keywords | glycosyltransferase, purine salvage, transferase |
Biological source | Toxoplasma gondii |
Cellular location | Cytoplasm: Q26997 |
Total number of polymer chains | 2 |
Total formula weight | 54588.64 |
Authors | Heroux, A.,White, E.L.,Ross, L.J.,Kuzin, A.P.,Borhani, D.W. (deposition date: 2000-09-08, release date: 2000-12-06, Last modification date: 2024-04-03) |
Primary citation | Heroux, A.,White, E.L.,Ross, L.J.,Kuzin, A.P.,Borhani, D.W. Substrate deformation in a hypoxanthine-guanine phosphoribosyltransferase ternary complex: the structural basis for catalysis. Structure Fold.Des., 8:1309-1318, 2000 Cited by PubMed: 11188695DOI: 10.1016/S0969-2126(00)00546-3 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.05 Å) |
Structure validation
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