1FKF

ATOMIC STRUCTURE OF FKBP-FK506, AN IMMUNOPHILIN-IMMUNOSUPPRESSANT COMPLEX

Summary for 1FKF

• Entry DOI: 10.2210/pdb1fkf/pdb
• Descriptor: FK506 BINDING PROTEIN, 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN (3 entities in total)
• Functional Keywords: isomerase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm, cytosol : P62942
• Total number of polymer chains: 1
• Total formula weight: 12640.53

Authors

Vanduyne, G.D.,Standaert, R.F.,Karplus, P.A.,Schreiber, S.L.,Clardy, J. (deposition date: 1991-05-07, release date: 1991-07-15, Last modification date: 2024-02-07)

• Primary citation: Van Duyne, G.D.,Standaert, R.F.,Karplus, P.A.,Schreiber, S.L.,Clardy, J.; Atomic structure of FKBP-FK506, an immunophilin-immunosuppressant complex.; Science, 252:839-842, 1991; PubMed: 1709302

Experimental method

X-RAY DIFFRACTION (1.7 Å)