1FKF

ATOMIC STRUCTURE OF FKBP-FK506, AN IMMUNOPHILIN-IMMUNOSUPPRESSANT COMPLEX

Experimental procedure

Spacegroup name	P 42 21 2
Unit cell lengths	58.070, 58.070, 55.650
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	10.000 - 1.700
R-factor	0.17 *
Rwork	0.170
RMSD bond length	0.010
RMSD bond angle	2.800
Refinement software	X-PLOR

Data quality characteristics

	Overall
High resolution limit [Å]	1.700 *
Rmerge	0.054 *
Total number of observations	69770 *
Number of reflections	10855 *
Completeness [%]	99.0 *

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	Vapor diffusion, hanging drop *	5.9 *

Crystallization Reagents in Literatures

ID	crystal ID	solution	reagent name	concentration (unit)	details
1	1	drop	protein-FK506 complex	10 (mg/ml)
2	1	reservoir		1.7 (M)
3	1	reservoir	phosphate	0.1 (M)