1F3M
CRYSTAL STRUCTURE OF HUMAN SERINE/THREONINE KINASE PAK1
Summary for 1F3M
Entry DOI | 10.2210/pdb1f3m/pdb |
Descriptor | SERINE/THREONINE-PROTEIN KINASE PAK-ALPHA, IODIDE ION, ... (4 entities in total) |
Functional Keywords | kinase domain, autoinhibitory fragment, homodimer, transferase |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm : Q13153 Q13153 |
Total number of polymer chains | 4 |
Total formula weight | 88460.21 |
Authors | Lei, M.,Lu, W.,Meng, W.,Parrini, M.-C.,Eck, M.J.,Mayer, B.J.,Harrison, S.C. (deposition date: 2000-06-05, release date: 2000-06-29, Last modification date: 2024-02-07) |
Primary citation | Lei, M.,Lu, W.,Meng, W.,Parrini, M.C.,Eck, M.J.,Mayer, B.J.,Harrison, S.C. Structure of PAK1 in an autoinhibited conformation reveals a multistage activation switch. Cell(Cambridge,Mass.), 102:387-397, 2000 Cited by PubMed: 10975528DOI: 10.1016/S0092-8674(00)00043-X PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
Download full validation report