1EK6

STRUCTURE OF HUMAN UDP-GALACTOSE 4-EPIMERASE COMPLEXED WITH NADH AND UDP-GLUCOSE

Summary for 1EK6

Entry DOI	10.2210/pdb1ek6/pdb
Related	1EK5
Descriptor	UDP-GALACTOSE 4-EPIMERASE, MAGNESIUM ION, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... (6 entities in total)
Functional Keywords	epimerase, short-chain dehydrogenase, galactosemia, isomerase
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	79383.74
Authors	Thoden, J.B.,Wohlers, T.M.,Fridovich-Keil, J.L.,Holden, H.M. (deposition date: 2000-03-06, release date: 2000-05-17, Last modification date: 2024-02-07)
Primary citation	Thoden, J.B.,Wohlers, T.M.,Fridovich-Keil, J.L.,Holden, H.M. Crystallographic evidence for Tyr 157 functioning as the active site base in human UDP-galactose 4-epimerase. Biochemistry, 39:5691-5701, 2000 Cited by PubMed: 10801319 DOI: 10.1021/bi000215l PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation