1DYH
ISOMORPHOUS CRYSTAL STRUCTURES OF ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE, 5-DEAZAFOLATE AND 5,10-DIDEAZATETRAHYDROFOLATE: MECHANISTIC IMPLICATIONS
Summary for 1DYH
Entry DOI | 10.2210/pdb1dyh/pdb |
Descriptor | DIHYDROFOLATE REDUCTASE, CHLORIDE ION, 5-DEAZAFOLIC ACID, ... (5 entities in total) |
Functional Keywords | oxidoreductase |
Biological source | Escherichia coli |
Total number of polymer chains | 2 |
Total formula weight | 37032.45 |
Authors | Reyes, V.M.,Kraut, J. (deposition date: 1994-10-26, release date: 1995-06-03, Last modification date: 2024-02-07) |
Primary citation | Reyes, V.M.,Sawaya, M.R.,Brown, K.A.,Kraut, J. Isomorphous crystal structures of Escherichia coli dihydrofolate reductase complexed with folate, 5-deazafolate, and 5,10-dideazatetrahydrofolate: mechanistic implications. Biochemistry, 34:2710-2723, 1995 Cited by PubMed: 7873554DOI: 10.1021/bi00008a039 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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