1DPX

STRUCTURE OF HEN EGG-WHITE LYSOZYME

Summary for 1DPX

Entry DOI	10.2210/pdb1dpx/pdb
Related	1DPW
Descriptor	LYSOZYME, CHLORIDE ION (3 entities in total)
Functional Keywords	protein-chloride complex, hydrolase
Biological source	Gallus gallus (chicken)
Cellular location	Secreted: P00698
Total number of polymer chains	1
Total formula weight	14402.07
Authors	Weiss, M.S.,Palm, G.J.,Hilgenfeld, R. (deposition date: 1999-12-28, release date: 2000-01-03, Last modification date: 2024-11-20)
Primary citation	Weiss, M.S.,Palm, G.J.,Hilgenfeld, R. Crystallization, structure solution and refinement of hen egg-white lysozyme at pH 8.0 in the presence of MPD. Acta Crystallogr.,Sect.D, 56:952-958, 2000 Cited by PubMed Abstract: Hen egg-white lysozyme has been crystallized at slightly alkaline pH using 2-methyl-2,4-pentanediol (MPD) as the precipitant. The crystals are nearly isomorphous to crystals grown at acidic pH using sodium chloride as the precipitant. However, the growth kinetics differ markedly between the two conditions. The major reason for this is a molecule of MPD that binds tightly in between two lysozyme molecules and favors the growth of the crystals along the crystallographic c direction over growth perpendicular to it. PubMed: 10944331 DOI: 10.1107/S0907444900006685 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.65 Å)

Structure validation