1DHI

LONG-RANGE STRUCTURAL EFFECTS IN A SECOND-SITE REVERTANT OF A MUTANT DIHYDROFOLATE REDUCTASE

Summary for 1DHI

Entry DOI	10.2210/pdb1dhi/pdb
Descriptor	DIHYDROFOLATE REDUCTASE, CHLORIDE ION, METHOTREXATE, ... (5 entities in total)
Functional Keywords	oxidoreductase
Biological source	Escherichia coli
Total number of polymer chains	2
Total formula weight	37004.49
Authors	Oatley, S.J.,Villafranca, J.E.,Brown, K.A.,Kraut, J. (deposition date: 1993-10-29, release date: 1994-01-31, Last modification date: 2024-02-07)
Primary citation	Brown, K.A.,Howell, E.E.,Kraut, J. Long-range structural effects in a second-site revertant of a mutant dihydrofolate reductase. Proc.Natl.Acad.Sci.USA, 90:11753-11756, 1993 Cited by PubMed: 8265622 DOI: 10.1073/pnas.90.24.11753 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation