1DDR

MOLECULE: DIHYDROFOLATE REDUCTASE (E.C.1.5.1.3) COMPLEXED WITH METHOTREXATE AND UREA

Summary for 1DDR

Entry DOI	10.2210/pdb1ddr/pdb
Descriptor	DIHYDROFOLATE REDUCTASE, CHLORIDE ION, METHOTREXATE, ... (6 entities in total)
Functional Keywords	oxido-reductase, oxidoreductase
Biological source	Escherichia coli
Total number of polymer chains	2
Total formula weight	37358.82
Authors	Yennawar, H.P.,Farber, G.K. (deposition date: 1995-06-29, release date: 1995-10-15, Last modification date: 2024-02-07)
Primary citation	Dunbar, J.,Yennawar, H.P.,Banerjee, S.,Luo, J.,Farber, G.K. The effect of denaturants on protein structure. Protein Sci., 6:1727-1733, 1997 Cited by PubMed: 9260285 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.45 Å)

Structure validation