1DDR
MOLECULE: DIHYDROFOLATE REDUCTASE (E.C.1.5.1.3) COMPLEXED WITH METHOTREXATE AND UREA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | DIHYDROFOLATE REDUCTASE | polymer | 159 | 18019.3 | 2 | UniProt (P0ABQ4) Pfam (PF00186) | Escherichia coli | |
| 2 | C, H (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 3 | D, J (A, B) | METHOTREXATE | non-polymer | 454.4 | 2 | Chemie (MTX) | |||
| 4 | E, F, G, K, L (A, B) | UREA | non-polymer | 60.1 | 5 | Chemie (URE) | |||
| 5 | I (B) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 6 | M, N (A, B) | water | water | 18.0 | 179 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 36038.7 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1320.1 | |
| All* | Total formula weight | 37358.8 |
