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1DDR

MOLECULE: DIHYDROFOLATE REDUCTASE (E.C.1.5.1.3) COMPLEXED WITH METHOTREXATE AND UREA

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BDIHYDROFOLATE REDUCTASEpolymer15918019.32UniProt (P0ABQ4)
Pfam (PF00186)
In PDB
Escherichia coli
2A, BCHLORIDE IONnon-polymer35.52Chemie (CL)
3A, BMETHOTREXATEnon-polymer454.42Chemie (MTX)
4A, BUREAnon-polymer60.15Chemie (URE)
5BCALCIUM IONnon-polymer40.11Chemie (CA)
6waterwater18.0179Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight36038.7
Non-Polymers*Number of molecules10
Total formula weight1320.1
All*Total formula weight37358.8
*Water molecules are not included.

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PDB entries from 2024-08-28

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