1DD6
IMP-1 METALLO BETA-LACTAMASE FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH A MERCAPTOCARBOXYLATE INHIBITOR
Summary for 1DD6
Entry DOI | 10.2210/pdb1dd6/pdb |
Related | 1DDK |
Descriptor | IMP-1 METALLO BETA-LACTAMASE, SULFATE ION, ZINC ION, ... (5 entities in total) |
Functional Keywords | metallo beta-lactamase inhibitor, mercaptocarboxylate inhibitor, imp-1 metallo beta-lactamase, hydrolase |
Biological source | Pseudomonas aeruginosa |
Cellular location | Periplasm : P52699 |
Total number of polymer chains | 2 |
Total formula weight | 51510.08 |
Authors | Concha, N.O.,Janson, C.A.,Rowling, P.,Pearson, S.,Cheever, C.A.,Clarke, B.P.,Lewis, C.,Galleni, M.,Frere, J.M.,Payne, D.J.,Bateson, J.H.,Abdel-Meguid, S.S. (deposition date: 1999-11-08, release date: 2000-11-08, Last modification date: 2024-02-07) |
Primary citation | Concha, N.O.,Janson, C.A.,Rowling, P.,Pearson, S.,Cheever, C.A.,Clarke, B.P.,Lewis, C.,Galleni, M.,Frere, J.M.,Payne, D.J.,Bateson, J.H.,Abdel-Meguid, S.S. Crystal structure of the IMP-1 metallo beta-lactamase from Pseudomonas aeruginosa and its complex with a mercaptocarboxylate inhibitor: binding determinants of a potent, broad-spectrum inhibitor. Biochemistry, 39:4288-4298, 2000 Cited by PubMed: 10757977DOI: 10.1021/bi992569m PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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